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Record Information
Version1.0
Creation Date2019-07-14 16:36:11 UTC
Last Updated2019-10-01 21:41:12 UTC
CypComp IDCC01993
Compound Information
NameNabumetone
Structure ImageBlxxjmdckkhmkv uhfffaoysa n
InChIKeyBLXXJMDCKKHMKV-UHFFFAOYSA-N
PubChem ID4409
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <16,15;Cleavage;R1>
  • <16,H;Oxidation;R1>
  • Not Available
  • <16,15;Cleavage;R1>
  • <16,H;Oxidation;R1>
  • Not Available
  • Not Available
  • <16,15;Cleavage;R1>
  • <16,H;Oxidation;R1>
  • <16,15;Cleavage;R1>
  • <16,H;Oxidation;R1>
  • <16,15;Cleavage;R1>
  • <16,H;Oxidation;R1>
  • Not Available
References
  1. Turpeinen M, Hofmann U, Klein K, Murdter T, Schwab M, Zanger UM: A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes. Drug Metab Dispos. 2009 May;37(5):1017-24. doi: 10.1124/dmd.108.025700. Epub 2009 Feb 9. [PubMed:19204080 ]
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