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Showing CypComp Card for CC01994: Naproxen (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:11 UTC
Last Updated2019-10-01 21:41:12 UTC
CypComp IDCC01994
Compound Information
NameNaproxen
Structure ImageCmwtzpsulfxxja vifpvbqesa n
InChIKeyCMWTZPSULFXXJA-VIFPVBQESA-N
PubChem ID156391
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <15,12;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • Not Available
  • Not Available
  • <15,12;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • <15,12;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
References
  1. Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR: Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation. Eur J Clin Pharmacol. 1997;52(4):293-8. [PubMed:9248768 ]
Download FileCC01994.sdf