Showing CypComp Card for CC01999: Nordiazepam (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:14 UTC
Last Updated2019-10-01 21:41:13 UTC
CypComp IDCC01999
Compound Information
NameNordiazepam
Structure ImageAkplhcdwdrpjgd uhfffaoysa n
InChIKeyAKPLHCDWDRPJGD-UHFFFAOYSA-N
PubChem ID2997
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <12,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <12,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • <12,H;Hydroxylation;R1>
References
  1. Yang TJ, Shou M, Korzekwa KR, Gonzalez FJ, Gelboin HV, Yang SK: Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam. Biochem Pharmacol. 1998 Mar 15;55(6):889-96. doi: 10.1016/s0006-2952(97)00558-3. [PubMed:9586962 ]
  2. Ono S, Hatanaka T, Miyazawa S, Tsutsui M, Aoyama T, Gonzalez FJ, Satoh T: Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily. Xenobiotica. 1996 Nov;26(11):1155-66. doi: 10.3109/00498259609050260. [PubMed:8948091 ]
Download FileCC01999.sdf