Showing CypComp Card for CC02023: Promazine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:22 UTC
Last Updated2019-10-01 21:41:16 UTC
CypComp IDCC02023
Compound Information
NamePromazine
Structure ImageZgugwuxljsttma uhfffaoysa n
InChIKeyZGUGWUXLJSTTMA-UHFFFAOYSA-N
PubChem ID4926
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
  • <10,S;S-Oxidation;R1>
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
  • Not Available
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
  • <10,S;S-Oxidation;R1>
  • <20,18;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <19,18;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <10,S;S-Oxidation;R3>
References
  1. Wojcikowski J, Pichard-Garcia L, Maurel P, Daniel WA: Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine. Br J Pharmacol. 2003 Apr;138(8):1465-74. doi: 10.1038/sj.bjp.0705195. [PubMed:12721102 ]
Download FileCC02023.sdf