Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:36:23 UTC |
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Last Updated | 2019-10-01 21:41:17 UTC |
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CypComp ID | CC02025 |
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Compound Information |
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Name | Propofol |
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Structure Image | |
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InChIKey | OLBCVFGFOZPWHH-UHFFFAOYSA-N |
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PubChem ID | 4943 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | |
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References | - Guitton J, Buronfosse T, Desage M, Flinois JP, Perdrix JP, Brazier JL, Beaune P: Possible involvement of multiple human cytochrome P450 isoforms in the liver metabolism of propofol. Br J Anaesth. 1998 Jun;80(6):788-95. doi: 10.1093/bja/80.6.788. [PubMed:9771309 ]
- Court MH, Duan SX, Hesse LM, Venkatakrishnan K, Greenblatt DJ: Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes. Anesthesiology. 2001 Jan;94(1):110-9. doi: 10.1097/00000542-200101000-00021. [PubMed:11135730 ]
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Download File | CC02025.sdf |
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