Showing CypComp Card for CC02029: Pyrazoloacridine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:24 UTC
Last Updated2019-10-01 21:41:17 UTC
CypComp IDCC02029
Compound Information
NamePyrazoloacridine
Structure ImageHzcwpkgytcjseb uhfffaoysa n
InChIKeyHZCWPKGYTCJSEB-UHFFFAOYSA-N
PubChem ID339455
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <24,22;Cleavage;R1>
  • <24,H;Oxidation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <26,25;Cleavage;R1>
  • <26,H;Oxidation;R1>
  • <27,25;Cleavage;R2>
  • <27,H;Oxidation;R2>
References
  1. Reid JM, Walker DL, Miller JK, Benson LM, Tomlinson AJ, Naylor S, Blajeski AL, LoRusso PM, Ames MM: The metabolism of pyrazoloacridine (NSC 366140) by cytochromes p450 and flavin monooxygenase in human liver microsomes. Clin Cancer Res. 2004 Feb 15;10(4):1471-80. [PubMed:14977851 ]
Download FileCC02029.sdf