Showing CypComp Card for CC02032: Ranitidine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:26 UTC
Last Updated2019-10-01 21:41:17 UTC
CypComp IDCC02032
Compound Information
NameRanitidine
Structure ImageVmxuwoksqnhoca ukthltgxsa n
InChIKeyVMXUWOKSQNHOCA-UKTHLTGXSA-N
PubChem ID3001055
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <9,7;Cleavage;R1>
  • <9,H;Oxidation;R1>
  • <10,7;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <9,7;Cleavage;R1>
  • <9,H;Oxidation;R1>
  • <10,7;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • <9,7;Cleavage;R1>
  • <9,H;Oxidation;R1>
  • <10,7;Cleavage;R2>
  • <10,H;Oxidation;R2>
  • Not Available
  • Not Available
References
  1. Chung WG, Park CS, Roh HK, Lee WK, Cha YN: Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450. Jpn J Pharmacol. 2000 Oct;84(2):213-20. [PubMed:11128045 ]
Download FileCC02032.sdf