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Record Information
Version1.0
Creation Date2019-07-14 16:36:27 UTC
Last Updated2019-10-01 21:41:18 UTC
CypComp IDCC02037
Compound Information
NameRosiglitazone
Structure ImageYasakcucglmorw hnnxbmfysa n
InChIKeyYASAKCUCGLMORW-HNNXBMFYSA-N
PubChem ID445655
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
  • <25,H;Hydroxylation;R2>
  • <21,H;Hydroxylation;R3>
  • Not Available
  • Not Available
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
  • <25,H;Hydroxylation;R2>
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
  • <25,H;Hydroxylation;R2>
  • Not Available
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
  • <25,H;Hydroxylation;R2>
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
  • <25,H;Hydroxylation;R2>
  • <23,9;Cleavage;R1>
  • <23,H;Oxidation;R1>
References
  1. Baldwin SJ, Clarke SE, Chenery RJ: Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone. Br J Clin Pharmacol. 1999 Sep;48(3):424-32. doi: 10.1046/j.1365-2125.1999.00030.x. [PubMed:10510156 ]
Download FileCC02037.sdf