Showing CypComp Card for CC02038: Rutaecarpine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:27 UTC
Last Updated2019-10-01 21:41:18 UTC
CypComp IDCC02038
Compound Information
NameRutaecarpine
Structure ImageAcvgwskvryfwrp uhfffaoysa n
InChIKeyACVGWSKVRYFWRP-UHFFFAOYSA-N
PubChem ID65752
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <22,H;Hydroxylation;R1>
  • <13,H;Hydroxylation;R2>
  • <14,H;Hydroxylation;R3>
  • <19,H;Hydroxylation;R4>
  • Not Available
  • Not Available
  • Not Available
  • <22,H;Hydroxylation;R1>
  • <13,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R3>
  • <14,H;Hydroxylation;R4>
  • <19,H;Hydroxylation;R5>
  • Not Available
  • <22,H;Hydroxylation;R1>
  • <13,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R3>
  • <19,H;Hydroxylation;R4>
  • Not Available
  • <22,H;Hydroxylation;R1>
  • <13,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R3>
  • <14,H;Hydroxylation;R4>
  • <19,H;Hydroxylation;R5>
References
  1. Lee SK, Lee JH, Yoo HH, Kim DH, Jahng Y, Jeong TC: Characterization of human liver cytochrome P450 enzymes involved in the metabolism of rutaecarpine. J Pharm Biomed Anal. 2006 Apr 11;41(1):304-9. doi: 10.1016/j.jpba.2005.10.039. Epub 2005 Nov 28. [PubMed:16318905 ]
  2. Ueng YF, Don MJ, Jan WC, Wang SY, Ho LK, Chen CF: Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450. Drug Metab Dispos. 2006 May;34(5):821-7. doi: 10.1124/dmd.105.007849. Epub 2006 Feb 24. [PubMed:16501007 ]
Download FileCC02038.sdf