Showing CypComp Card for CC02056: Thioridazine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:34 UTC
Last Updated2019-10-01 21:41:20 UTC
CypComp IDCC02056
Compound Information
NameThioridazine
Structure ImageKlbqzwritkrqqv mrxnpfedsa n
InChIKeyKLBQZWRITKRQQV-MRXNPFEDSA-N
PubChem ID6604030
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <14,S;S-Oxidation;R1>
  • <3,S;S-Oxidation;R2>
  • <16,8;Cleavage;R3>
  • <16,H;Oxidation;R3>
  • <3,S;S-Oxidation;R1>
  • <3,S;S-Oxidation;R1>
  • <14,S;S-Oxidation;R2>
  • Not Available
  • <3,S;S-Oxidation;R1>
  • <14,S;S-Oxidation;R2>
  • <14,S;S-Oxidation;R1>
  • <3,S;S-Oxidation;R2>
  • <16,8;Cleavage;R3>
  • <16,H;Oxidation;R3>
  • <14,S;S-Oxidation;R1>
  • <3,S;S-Oxidation;R2>
  • <16,8;Cleavage;R3>
  • <16,H;Oxidation;R3>
  • <3,S;S-Oxidation;R1>
  • <14,S;S-Oxidation;R1>
  • <3,S;S-Oxidation;R2>
  • <16,8;Cleavage;R3>
  • <16,H;Oxidation;R3>
References
  1. Wojcikowski J, Maurel P, Daniel WA: Characterization of human cytochrome p450 enzymes involved in the metabolism of the piperidine-type phenothiazine neuroleptic thioridazine. Drug Metab Dispos. 2006 Mar;34(3):471-6. doi: 10.1124/dmd.105.006445. Epub 2005 Nov 4. [PubMed:16272405 ]
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