Showing CypComp Card for CC02057: Ticlopidine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:34 UTC
Last Updated2019-10-01 21:41:21 UTC
CypComp IDCC02057
Compound Information
NameTiclopidine
Structure ImagePhwboxqywznqin uhfffaoysa n
InChIKeyPHWBOXQYWZNQIN-UHFFFAOYSA-N
PubChem ID5472
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
  • Not Available
  • Not Available
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
  • Not Available
  • <3,H;Oxidation;R1>
  • <2,3;Reduction;R1>
  • <2,1;Oxidation;R1>
  • <1,5;Reduction;R1>
References
  1. Dansette PM, Libraire J, Bertho G, Mansuy D: Metabolic oxidative cleavage of thioesters: evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and clopidogrel. Chem Res Toxicol. 2009 Feb;22(2):369-73. doi: 10.1021/tx8004828. [PubMed:19170597 ]
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