Showing CypComp Card for CC02060: Toremifene (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:35 UTC
Last Updated2019-10-01 21:41:21 UTC
CypComp IDCC02060
Compound Information
NameToremifene
Structure ImageXfcljvaboiyomf qplcgjkrsa n
InChIKeyXFCLJVABOIYOMF-QPLCGJKRSA-N
PubChem ID3005573
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <19,18;Cleavage;R1>
  • <19,H;Oxidation;R1>
  • <20,18;Cleavage;R2>
  • <20,H;Oxidation;R2>
  • <17,18;Cleavage;R3>
  • <17,H;Oxidation;R3>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <19,18;Cleavage;R1>
  • <19,H;Oxidation;R1>
  • <20,18;Cleavage;R2>
  • <20,H;Oxidation;R2>
  • <17,18;Cleavage;R3>
  • <17,H;Oxidation;R3>
References
  1. Berthou F, Dreano Y, Belloc C, Kangas L, Gautier JC, Beaune P: Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes. Biochem Pharmacol. 1994 May 18;47(10):1883-95. doi: 10.1016/0006-2952(94)90319-0. [PubMed:8204106 ]
Download FileCC02060.sdf