Showing CypComp Card for CC02070: Zolpidem (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:40 UTC
Last Updated2019-10-01 21:41:22 UTC
CypComp IDCC02070
Compound Information
NameZolpidem
Structure ImageZafyathczyhlpb uhfffaoysa n
InChIKeyZAFYATHCZYHLPB-UHFFFAOYSA-N
PubChem ID5732
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <18,H;Hydroxylation;R1>
  • <23,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • Not Available
  • Not Available
  • Not Available
  • <18,H;Hydroxylation;R1>
  • <23,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R1>
  • <23,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R1>
  • <23,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • Not Available
  • <18,H;Hydroxylation;R1>
  • <23,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • <21,H;Hydroxylation;R3>
  • <20,H;Hydroxylation;R4>
References
  1. Von Moltke LL, Greenblatt DJ, Granda BW, Duan SX, Grassi JM, Venkatakrishnan K, Harmatz JS, Shader RI: Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations. Br J Clin Pharmacol. 1999 Jul;48(1):89-97. doi: 10.1046/j.1365-2125.1999.00953.x. [PubMed:10383565 ]
  2. Wang B, Zhou SF: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218. [PubMed:19754423 ]
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