Showing CypComp Card for CC02082: DETC-Me (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:44 UTC
Last Updated2019-10-01 21:41:24 UTC
CypComp IDCC02082
Compound Information
NameDETC-Me
Structure ImageAqtfqqhfhgbcpg uhfffaoysa n
InChIKeyAQTFQQHFHGBCPG-UHFFFAOYSA-N
PubChem ID119467
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <8,S;S-Oxidation;R1>
  • <8,S;S-Oxidation;R1>
  • <8,S;S-Oxidation;R1>
  • Not Available
  • <8,S;S-Oxidation;R1>
  • Not Available
  • <8,S;S-Oxidation;R1>
  • <8,S;S-Oxidation;R1>
  • <8,S;S-Oxidation;R1>
References
  1. Madan A, Parkinson A, Faiman MD: Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram. Drug Metab Dispos. 1995 Oct;23(10):1153-62. [PubMed:8654205 ]
Download FileCC02082.sdf