Showing CypComp Card for CC02105: Flunarizine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:51 UTC
Last Updated2019-10-01 21:41:27 UTC
CypComp IDCC02105
Compound Information
NameFlunarizine
Structure ImageSmanxxcatutddt qpjjxvbhsa n
InChIKeySMANXXCATUTDDT-QPJJXVBHSA-N
PubChem ID941361
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <4,5;Cleavage;R1>
  • <4,H;Oxidation;R1>
  • <14,13;Cleavage;R2>
  • <14,H;Oxidation;R2>
  • <4,5;Cleavage;R1>
  • <4,H;Oxidation;R1>
  • <14,13;Cleavage;R2>
  • <14,H;Oxidation;R2>
  • Not Available
  • Not Available
  • <4,5;Cleavage;R1>
  • <4,H;Oxidation;R1>
  • <14,13;Cleavage;R2>
  • <14,H;Oxidation;R2>
  • Not Available
  • <8,H;Hydroxylation;R1>
  • Not Available
  • Not Available
References
  1. Kariya S, Isozaki S, Uchino K, Suzuki T, Narimatsu S: Oxidative metabolism of flunarizine and cinnarizine by microsomes from B-lymphoblastoid cell lines expressing human cytochrome P450 enzymes. Biol Pharm Bull. 1996 Nov;19(11):1511-4. [PubMed:8951176 ]
Download FileCC02105.sdf