Showing CypComp Card for CC02130: Diazepam (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:00 UTC
Last Updated2019-10-01 21:41:30 UTC
CypComp IDCC02130
Compound Information
NameDiazepam
Structure ImageAaovkjbebidnhe uhfffaoysa n
InChIKeyAAOVKJBEBIDNHE-UHFFFAOYSA-N
PubChem ID3016
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • <10,9;Cleavage;R1>
  • <10,H;Oxidation;R1>
  • <10,9;Cleavage;R1>
  • <10,H;Oxidation;R1>
  • <10,9;Cleavage;R1>
  • <10,H;Oxidation;R1>
  • <10,9;Cleavage;R1>
  • <10,H;Oxidation;R1>
  • <13,H;Hydroxylation;R2>
  • Not Available
  • Not Available
  • <10,9;Cleavage;R1>
  • <10,H;Oxidation;R1>
  • <13,H;Hydroxylation;R2>
References
  1. Yang TJ, Krausz KW, Sai Y, Gonzalez FJ, Gelboin HV: Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism. Drug Metab Dispos. 1999 Jan;27(1):102-9. [PubMed:9884317 ]
Download FileCC02130.sdf