Showing CypComp Card for CC02138: Loperamide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:02 UTC
Last Updated2019-10-01 21:41:31 UTC
CypComp IDCC02138
Compound Information
NameLoperamide
Structure ImageRdoiqahitmmdaj uhfffaoysa n
InChIKeyRDOIQAHITMMDAJ-UHFFFAOYSA-N
PubChem ID3955
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • <18,11;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <19,11;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • <18,11;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <19,11;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • Not Available
  • Not Available
  • <18,11;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <19,11;Cleavage;R2>
  • <19,H;Oxidation;R2>
  • Not Available
  • <18,11;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <19,11;Cleavage;R2>
  • <19,H;Oxidation;R2>
References
  1. Kim KA, Chung J, Jung DH, Park JY: Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes. Eur J Clin Pharmacol. 2004 Oct;60(8):575-81. doi: 10.1007/s00228-004-0815-3. Epub 2004 Sep 8. [PubMed:15365656 ]
Download FileCC02138.sdf