Showing CypComp Card for CC02144: Nevirapine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:04 UTC
Last Updated2019-10-01 21:41:31 UTC
CypComp IDCC02144
Compound Information
NameNevirapine
Structure ImageNqdjxkovjztuja uhfffaoysa n
InChIKeyNQDJXKOVJZTUJA-UHFFFAOYSA-N
PubChem ID4463
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • <5,H;Hydroxylation;R1>
  • <15,H;Hydroxylation;R2>
  • Not Available
  • <19,H;Hydroxylation;R1>
  • Not Available
  • <5,H;Hydroxylation;R1>
  • <19,H;Hdroxylation;R2>
  • Not Available
  • <5,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R2>
  • <19,H;Hydroxylaton;R3>
References
  1. Erickson DA, Mather G, Trager WF, Levy RH, Keirns JJ: Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450. Drug Metab Dispos. 1999 Dec;27(12):1488-95. [PubMed:10570031 ]
Download FileCC02144.sdf