Showing CypComp Card for CC02157: 2'-Hydroxy-indomethacin-phenethylamide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:09 UTC
Last Updated2019-10-01 21:41:33 UTC
CypComp IDCC02157
Compound Information
Name2'-Hydroxy-indomethacin-phenethylamide
Structure ImageAoiqkshkqijfmk ruzdidtesa n
InChIKeyAOIQKSHKQIJFMK-RUZDIDTESA-N
PubChem ID44274898
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <20,16;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • <20,16;Cleavage;R1>
  • <20,H;Oxidation;R1>
  • Not Available
  • <27,28;Oxidation;R1>
References
  1. Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ: Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites. Drug Metab Dispos. 2004 Jan;32(1):113-22. doi: 10.1124/dmd.32.1.113. [PubMed:14709628 ]
Download FileCC02157.sdf