Showing CypComp Card for CC02159: DRF-4367 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:10 UTC
Last Updated2019-10-01 21:41:33 UTC
CypComp IDCC02159
Compound Information
NameDRF-4367
Structure ImageMvznvbxatdcmmj uhfffaoysa n
InChIKeyMVZNVBXATDCMMJ-UHFFFAOYSA-N
PubChem ID9802596
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • Not Available
  • Not Available
References
  1. Muzeeb S, Basha SJ, Shashikumar D, Mullangi R, Srinivas NR: Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT1A1, 1A3 and 1A8. Eur J Drug Metab Pharmacokinet. 2006 Oct-Dec;31(4):299-309. doi: 10.1007/BF03190471. [PubMed:17315542 ]
Download FileCC02159.sdf