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Record Information
Version1.0
Creation Date2019-07-14 16:37:12 UTC
Last Updated2019-10-01 21:41:34 UTC
CypComp IDCC02167
Compound Information
NameAmodiaquine
Structure ImageOvcdsshsilbfbn uhfffaoysa n
InChIKeyOVCDSSHSILBFBN-UHFFFAOYSA-N
PubChem ID2165
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <18,17;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <20,17;Cleavage;R2>
  • <20,H;Oxidation;R2>
  • Not Available
  • <18,17;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <20,17;Cleavage;R2>
  • <20,H;Oxidation;R2>
  • <18,17;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <20,17;Cleavage;R2>
  • <20,H;Oxidation;R2>
  • Not Available
  • <18,17;Cleavage;R1>
  • <18,H;Oxidation;R1>
  • <20,17;Cleavage;R2>
  • <20,H;Oxidation;R2>
References
  1. Li XQ, Bjorkman A, Andersson TB, Ridderstrom M, Masimirembwa CM: Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate. J Pharmacol Exp Ther. 2002 Feb;300(2):399-407. doi: 10.1124/jpet.300.2.399. [PubMed:11805197 ]
Download FileCC02167.sdf