Showing CypComp Card for CC02169: Chlorproguanil (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:13 UTC
Last Updated2019-10-01 21:41:35 UTC
CypComp IDCC02169
Compound Information
NameChlorproguanil
Structure ImageIsznzkhcrkxxau uhfffaoysa n
InChIKeyISZNZKHCRKXXAU-UHFFFAOYSA-N
PubChem ID22323
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <2,10;Cyclization;R1>
  • Not Available
  • Not Available
  • Not Available
References
  1. Wright JD, Helsby NA, Ward SA: The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides. Br J Clin Pharmacol. 1995 Apr;39(4):441-4. doi: 10.1111/j.1365-2125.1995.tb04474.x. [PubMed:7640152 ]
  2. Arfeen M, Patel DS, Abbat S, Taxak N, Bharatam PV: Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil. J Comput Chem. 2014 Oct 30;35(28):2047-55. doi: 10.1002/jcc.23719. Epub 2014 Sep 5. [PubMed:25196060 ]
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