Showing CypComp Card for CC02180: Hexobarbital (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:17 UTC
Last Updated2019-10-01 21:41:36 UTC
CypComp IDCC02180
Compound Information
NameHexobarbital
Structure ImageUyxawhwodhrrmr lbprgkrzsa n
InChIKeyUYXAWHWODHRRMR-LBPRGKRZSA-N
PubChem ID7036944
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <14,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
References
  1. Saito K, Dan H, Masuda K, Katsu T, Hanioka N, Yamamoto S, Miyano K, Yamano S, Narimatsu S: Stereoselective hexobarbital 3'-hydroxylation by CYP2C19 expressed in yeast cells and the roles of amino acid residues at positions 300 and 476. Chirality. 2007 Jul;19(7):550-8. doi: 10.1002/chir.20412. [PubMed:17487889 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Download FileCC02180.sdf