Showing CypComp Card for CC02184: Lansoprazole (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:18 UTC
Last Updated2019-10-01 21:41:36 UTC
CypComp IDCC02184
Compound Information
NameLansoprazole
Structure ImageMjihnnlfokezew ruzdidtesa n
InChIKeyMJIHNNLFOKEZEW-RUZDIDTESA-N
PubChem ID9578005
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <5,H;Hydroxylation;R1>
  • <6,H;Hydroxylation;R2>
  • <5,H;Hydroxylation;R1>
  • <6,H;Hydroxylation;R2>
  • Not Available
  • Not Available
  • <5,H;Hydroxylation;R1>
  • <6,H;Hydroxylation;R2>
  • <10,S;S-Oxidation;R3>
References
  1. Kim KA, Kim MJ, Park JY, Shon JH, Yoon YR, Lee SS, Liu KH, Chun JH, Hyun MH, Shin JG: Stereoselective metabolism of lansoprazole by human liver cytochrome P450 enzymes. Drug Metab Dispos. 2003 Oct;31(10):1227-34. doi: 10.1124/dmd.31.10.1227. [PubMed:12975331 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Download FileCC02184.sdf