Showing CypComp Card for CC02187: Muraglitazar (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:19 UTC
Last Updated2019-10-01 21:41:37 UTC
CypComp IDCC02187
Compound Information
NameMuraglitazar
Structure ImageIrlwjillxjgjtd uhfffaoysa n
InChIKeyIRLWJILLXJGJTD-UHFFFAOYSA-N
PubChem ID206044
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <14,1;Cleavage;R1>
  • <14,H;Oxidation;R1>
  • <24,H;Hydroxylation;R2>
  • <38,7;Cleavage;R3>
  • <38,H;Oxidation;R3>
  • <9,22;Reduction;R4>
  • <24,H;Hydroxylation;R1>
  • <9,22;Reduction;R2>
  • <24,H;Hydroxylation;R1>
  • <32,H;Hydroxylation;R2>
  • <14,1;Cleavage;R1>
  • <14,H;Oxidation;R1>
  • <38,7;Cleavage;R2>
  • <38,H;Oxidation;R2>
  • <9,22;Reduction;R3>
  • Not Available
  • <10,H;Hydroxylation;R1>
  • <14,1;Cleavage;R2>
  • <14,H;Oxidation;R2>
  • <24,H;Hydroxylation;R3>
  • <16,13;Cleavage;R4>
References
  1. Zhang D, Wang L, Chandrasena G, Ma L, Zhu M, Zhang H, Davis CD, Humphreys WG: Involvement of multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes in the in vitro metabolism of muraglitazar. Drug Metab Dispos. 2007 Jan;35(1):139-49. doi: 10.1124/dmd.106.011932. Epub 2006 Oct 24. [PubMed:17062778 ]
Download FileCC02187.sdf