Showing CypComp Card for CC02200: Trimipramine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:23 UTC
Last Updated2019-10-01 21:41:38 UTC
CypComp IDCC02200
Compound Information
NameTrimipramine
Structure ImageZscdbowyzjwbiy mrxnpfedsa n
InChIKeyZSCDBOWYZJWBIY-MRXNPFEDSA-N
PubChem ID5282594
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <21,20;Cleavage;R1>
  • <21,H;Oxidation;R1>
  • <22,20;Cleavage;R2>
  • <22,H;Oxidation;R2>
  • <10,H;Hydroxylation;R1>
  • <13,H;Hydroxylation;R2>
  • <18,H;Hydroxylation;R3>
  • <19,H;Hydroxylation;R4>
  • Not Available
  • Not Available
References
  1. Eap CB, Bender S, Gastpar M, Fischer W, Haarmann C, Powell K, Jonzier-Perey M, Cochard N, Baumann P: Steady state plasma levels of the enantiomers of trimipramine and of its metabolites in CYP2D6-, CYP2C19- and CYP3A4/5-phenotyped patients. Ther Drug Monit. 2000 Apr;22(2):209-14. [PubMed:10774635 ]
  2. Zhou SF: Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II. Clin Pharmacokinet. 2009;48(12):761-804. doi: 10.2165/11318070-000000000-00000. [PubMed:19902987 ]
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