Showing CypComp Card for CC02208: Taxol (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:25 UTC
Last Updated2019-10-01 21:41:39 UTC
CypComp IDCC02208
Compound Information
NameTaxol
Structure ImageRciniconznjxqf yukvppsfsa n
InChIKeyRCINICONZNJXQF-YUKVPPSFSA-N
PubChem ID14060306
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <14,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <57,H;Hydroxylation;R2>
References
  1. Sonnichsen DS, Liu Q, Schuetz EG, Schuetz JD, Pappo A, Relling MV: Variability in human cytochrome P450 paclitaxel metabolism. J Pharmacol Exp Ther. 1995 Nov;275(2):566-75. [PubMed:7473140 ]
  2. Harris JW, Rahman A, Kim BR, Guengerich FP, Collins JM: Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res. 1994 Aug 1;54(15):4026-35. [PubMed:7913410 ]
Download FileCC02208.sdf