Showing CypComp Card for CC02210: Cerivastatin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:26 UTC
Last Updated2019-10-01 21:41:39 UTC
CypComp IDCC02210
Compound Information
NameCerivastatin
Structure ImageSeerziqquaztol anmdkaqqsa n
InChIKeySEERZIQQUAZTOL-ANMDKAQQSA-N
PubChem ID446156
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <16,H;Hydroxylation;R1>
  • <19,H;Hydroxylation;R2>
  • <33,32;Cleavage;R3>
  • <33,H;Oxidation;R3>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <33,32;Cleavage;R1>
  • <33,H;Oxidation;R1>
References
  1. Muck W: Clinical pharmacokinetics of cerivastatin. Clin Pharmacokinet. 2000 Aug;39(2):99-116. doi: 10.2165/00003088-200039020-00002. [PubMed:10976657 ]
  2. Boberg M, Angerbauer R, Fey P, Kanhai WK, Karl W, Kern A, Ploschke J, Radtke M: Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved. Drug Metab Dispos. 1997 Mar;25(3):321-31. [PubMed:9172950 ]
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