Showing CypComp Card for CC02217: Licofelone-M1 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:28 UTC
Last Updated2019-10-01 21:41:40 UTC
CypComp IDCC02217
Compound Information
NameLicofelone-M1
Structure ImageYxniwvfdfgnced nnvcndcrsa n
InChIKeyYXNIWVFDFGNCED-NNVCNDCRSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <13,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R2>
  • <13,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R2>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
References
  1. Albrecht W, Unger A, Nussler AK, Laufer S: In vitro metabolism of 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid (licofelone, ML3000), an inhibitor of cyclooxygenase-1 and -2 and 5-lipoxygenase. Drug Metab Dispos. 2008 May;36(5):894-903. doi: 10.1124/dmd.108.020347. Epub 2008 Feb 11. [PubMed:18268076 ]
Download FileCC02217.sdf