Showing CypComp Card for CC02222: Repaglinide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:30 UTC
Last Updated2019-10-01 21:41:40 UTC
CypComp IDCC02222
Compound Information
NameRepaglinide
Structure ImageFaekwtjyaymjkf qhcpkhfhsa n
InChIKeyFAEKWTJYAYMJKF-QHCPKHFHSA-N
PubChem ID65981
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <7,3;Cleavage;R1>
  • <7,H;Oxidation;R1>
  • <8,3;Cleavage;R2>
  • <8,H;Oxdation;R2>
  • <13,H;Hydroxylation;R3>
  • <14,H;Hydroxylation;R4>
  • <16,H;Hydroxylation;R5>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <7,3;Cleavage;R1>
  • <7,H;Oxidation;R1>
  • <8,3;Cleavage;R2>
  • <8,H;Oxdation;R2>
  • <13,H;Hydroxylation;R3>
  • <14,H;Hydroxylation;R4>
  • <16,H;Hydroxylation;R5>
  • <30,28;Cleavage;R6>
  • <30,H;Oxidation;R6>
References
  1. Bidstrup TB, Bjornsdottir I, Sidelmann UG, Thomsen MS, Hansen KT: CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide. Br J Clin Pharmacol. 2003 Sep;56(3):305-14. doi: 10.1046/j.0306-5251.2003.01862.x. [PubMed:12919179 ]
Download FileCC02222.sdf