Showing CypComp Card for CC02225: Torasemide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:31 UTC
Last Updated2019-10-01 21:41:41 UTC
CypComp IDCC02225
Compound Information
NameTorasemide
Structure ImageNgbfqhcmquljnz uhfffaoysa n
InChIKeyNGBFQHCMQULJNZ-UHFFFAOYSA-N
PubChem ID41781
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • <22,H;Hydroxylation;R1>
  • <22,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
References
  1. Miners JO, Coulter S, Birkett DJ, Goldstein JA: Torsemide metabolism by CYP2C9 variants and other human CYP2C subfamily enzymes. Pharmacogenetics. 2000 Apr;10(3):267-70. [PubMed:10803683 ]
  2. Miners JO, Rees DL, Valente L, Veronese ME, Birkett DJ: Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism. J Pharmacol Exp Ther. 1995 Mar;272(3):1076-81. [PubMed:7891318 ]
Download FileCC02225.sdf