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Showing CypComp Card for CC02237: Losartan (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:33 UTC
Last Updated2019-10-01 21:41:42 UTC
CypComp IDCC02237
Compound Information
NameLosartan
Structure ImagePsifnnkumbgkdq uhfffaoysa n
InChIKeyPSIFNNKUMBGKDQ-UHFFFAOYSA-N
PubChem ID3961
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <24,H;Hydroxylation;R1>
  • <26,H;Hydroxylation;R2>
  • <29,30;Oxidation;R3>
  • Not Available
  • Not Available
  • Not Available
  • <24,H;Hydroxylation;R1>
  • <26,H;Hydroxylation;R2>
  • <29,30;Oxidation;R3>
References
  1. Stearns RA, Chakravarty PK, Chen R, Chiu SH: Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members. Drug Metab Dispos. 1995 Feb;23(2):207-15. [PubMed:7736913 ]
Download FileCC02237.sdf