Showing CypComp Card for CC02245: Valdecoxib (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:35 UTC
Last Updated2019-10-01 21:41:43 UTC
CypComp IDCC02245
Compound Information
NameValdecoxib
Structure ImageLnpdtqafdnkshk uhfffaoysa n
InChIKeyLNPDTQAFDNKSHK-UHFFFAOYSA-N
PubChem ID119607
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <10,H;Hydroxylation;R1>
  • <15,H;Hydroxylation;R2>
  • <16,H;Hydroxylation;R3>
  • Not Available
  • Not Available
  • Not Available
  • <10,H;Hydroxylation;R1>
  • <15,H;Hydroxylation;R2>
  • <16,H;Hydroxylation;R3>
References
  1. Ibrahim A, Park S, Feldman J, Karim A, Kharasch ED: Effects of parecoxib, a parenteral COX-2-specific inhibitor, on the pharmacokinetics and pharmacodynamics of propofol. Anesthesiology. 2002 Jan;96(1):88-95. doi: 10.1097/00000542-200201000-00020. [PubMed:11753007 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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