Showing CypComp Card for CC02253: Irbesartan (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:37 UTC
Last Updated2019-10-01 21:41:44 UTC
CypComp IDCC02253
Compound Information
NameIrbesartan
Structure ImageYoshytlcdandan uhfffaoysa n
InChIKeyYOSHYTLCDANDAN-UHFFFAOYSA-N
PubChem ID3749
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <3,H;Hydroxylation;R1>
  • <4,H;Hydroxylation;R2>
  • <14,H;Hydroxylation;R3>
  • <15,H;Oxidation;R4>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
References
  1. Chando TJ, Everett DW, Kahle AD, Starrett AM, Vachharajani N, Shyu WC, Kripalani KJ, Barbhaiya RH: Biotransformation of irbesartan in man. Drug Metab Dispos. 1998 May;26(5):408-17. [PubMed:9571222 ]
  2. Bourrie M, Meunier V, Berger Y, Fabre G: Role of cytochrome P-4502C9 in irbesartan oxidation by human liver microsomes. Drug Metab Dispos. 1999 Feb;27(2):288-96. [PubMed:9929518 ]
Download FileCC02253.sdf