Showing CypComp Card for CC02270: Astemizole (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:41 UTC
Last Updated2019-10-01 21:41:46 UTC
CypComp IDCC02270
Compound Information
NameAstemizole
Structure ImageGxdalqbwzgodgz uhfffaoysa n
InChIKeyGXDALQBWZGODGZ-UHFFFAOYSA-N
PubChem ID2247
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <11,H;Hydroxylation;R1>
  • <34,33;Cleavage;R2>
  • <34,H;Oxidation;R2>
  • Not Available
  • <11,H;Hydroxylation;R1>
  • <25,23;Cleavage;R2>
  • <25,H;Oxidation;R2>
References
  1. Matsumoto S, Yamazoe Y: Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine. Br J Clin Pharmacol. 2001 Feb;51(2):133-42. doi: 10.1111/j.1365-2125.2001.01292.x. [PubMed:11259984 ]
Download FileCC02270.sdf