Showing CypComp Card for CC02277: Delavirdine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:42 UTC
Last Updated2019-10-01 21:41:47 UTC
CypComp IDCC02277
Compound Information
NameDelavirdine
Structure ImageWhbigikbnxzkfe uhfffaoysa n
InChIKeyWHBIGIKBNXZKFE-UHFFFAOYSA-N
PubChem ID5625
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <30,29;Cleavage;R1>
  • <30,H;Oxidation;R1>
  • Not Available
  • <30,29;Cleavage;R1>
  • <30,H;Oxidation;R1>
  • <27,H;Oxidation;R2>
  • <27,28;Reduction;R2>
  • <28,23;Oxidation;R2>
  • <23,24;Reduction;R2>
  • <24,25;Reduction;R2>
  • <25,26;Oxidation;R2>
  • <26,27;Reduction;R2>
  • <24,29;Oxidation;R2>
References
  1. Voorman RL, Maio SM, Hauer MJ, Sanders PE, Payne NA, Ackland MJ: Metabolism of delavirdine, a human immunodeficiency virus type-1 reverse transcriptase inhibitor, by microsomal cytochrome P450 in humans, rats, and other species: probable involvement of CYP2D6 and CYP3A. Drug Metab Dispos. 1998 Jul;26(7):631-9. [PubMed:9660845 ]
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