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Record Information
Version1.0
Creation Date2019-07-14 16:37:43 UTC
Last Updated2019-10-01 21:41:47 UTC
CypComp IDCC02280
Compound Information
NameEzlopitant
Structure ImageXpnmcdyoyikvgb consdprksa n
InChIKeyXPNMCDYOYIKVGB-CONSDPRKSA-N
PubChem ID188927
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <32,H;Hydroxylation;R1>
  • <33,32;Dehydrogenation;R2>
  • <34,32;Dehydrogenation;R3>
  • Not Available
  • <32,H;Hydroxylation;R1>
  • <33,32;Dehydrogenation;R2>
  • <34,32;Dehydrogenation;R3>
References
  1. Obach RS: Metabolism of ezlopitant, a nonpeptidic substance P receptor antagonist, in liver microsomes: enzyme kinetics, cytochrome P450 isoform identity, and in vitro-in vivo correlation. Drug Metab Dispos. 2000 Sep;28(9):1069-76. [PubMed:10950851 ]
Download FileCC02280.sdf