Showing CypComp Card for CC02287: Mequitazine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:45 UTC
Last Updated2019-10-01 21:41:48 UTC
CypComp IDCC02287
Compound Information
NameMequitazine
Structure ImageFxksimklxmwgef uhfffaoysa n
InChIKeyFXKSIMKLXMWGEF-UHFFFAOYSA-N
PubChem ID15662541
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <10,S;S-Oxidation;R1>
  • <18,H;Hydroxylation;R2>
  • <19,H;Hydroxylation;R3>
  • Not Available
  • Not Available
References
  1. Nakamura K, Yokoi T, Kodama T, Inoue K, Nagashima K, Shimada N, Shimizu T, Kamataki T: Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes. J Pharmacol Exp Ther. 1998 Feb;284(2):437-42. [PubMed:9454781 ]
Download FileCC02287.sdf