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Record Information
Version1.0
Creation Date2019-07-14 16:37:48 UTC
Last Updated2019-10-01 21:41:50 UTC
CypComp IDCC02299
Compound Information
NameTamsulosin
Structure ImageDrhkjlxjiqtdtd oahllokosa n
InChIKeyDRHKJLXJIQTDTD-OAHLLOKOSA-N
PubChem ID129211
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <25,H;Hydroxylation;R1>
  • <12,6;Cleavage;R2>
  • <12,H;Oxidation;R2>
  • Not Available
  • <27,24;Cleavage;R1>
  • <27,H;Oxidation;R1>
  • <17,15;Cleavage;R2>
  • <17,H;Oxidation;R2>
References
  1. Kamimura H, Oishi S, Matsushima H, Watanabe T, Higuchi S, Hall M, Wood SG, Chasseaud LF: Identification of cytochrome P450 isozymes involved in metabolism of the alpha1-adrenoceptor blocker tamsulosin in human liver microsomes. Xenobiotica. 1998 Oct;28(10):909-22. doi: 10.1080/004982598238985. [PubMed:9849639 ]
Download FileCC02299.sdf