Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:37:48 UTC |
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Last Updated | 2019-10-01 21:41:50 UTC |
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CypComp ID | CC02299 |
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Compound Information |
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Name | Tamsulosin |
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Structure Image | |
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InChIKey | DRHKJLXJIQTDTD-OAHLLOKOSA-N |
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PubChem ID | 129211 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | - <25,H;Hydroxylation;R1>
- <12,6;Cleavage;R2>
- <12,H;Oxidation;R2>
| | - <27,24;Cleavage;R1>
- <27,H;Oxidation;R1>
- <17,15;Cleavage;R2>
- <17,H;Oxidation;R2>
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References | - Kamimura H, Oishi S, Matsushima H, Watanabe T, Higuchi S, Hall M, Wood SG, Chasseaud LF: Identification of cytochrome P450 isozymes involved in metabolism of the alpha1-adrenoceptor blocker tamsulosin in human liver microsomes. Xenobiotica. 1998 Oct;28(10):909-22. doi: 10.1080/004982598238985. [PubMed:9849639 ]
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Download File | CC02299.sdf |
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