Record Information
Version1.0
Creation Date2019-07-14 16:37:49 UTC
Last Updated2019-10-01 21:41:50 UTC
CypComp IDCC02300
Compound Information
NameTerfenadine
Structure ImageGugoeexeswieri pmerelpusa n
InChIKeyGUGOEEXESWIERI-PMERELPUSA-N
PubChem ID6604035
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <34,H;Hydroxylation;R1>
  • <33,H;Hydroxylation;R2>
  • <32,H;Hydroxylation;R3>
  • Not Available
  • <34,H;Hydroxylation;R1>
  • <33,H;Hydroxylation;R2>
  • <32,H;Hydroxylation;R3>
  • <21,20;Cleavage;R4>
  • <21,H;Oxidation;R4>
References
  1. Jones BC, Hyland R, Ackland M, Tyman CA, Smith DA: Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6. Drug Metab Dispos. 1998 Sep;26(9):875-82. [PubMed:9733666 ]
Download FileCC02300.sdf