Showing CypComp Card for CC02302: Traxoprodil (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:49 UTC
Last Updated2019-10-01 21:41:50 UTC
CypComp IDCC02302
Compound Information
NameTraxoprodil
Structure ImageQemsvzntsxpfja hnayvobhsa n
InChIKeyQEMSVZNTSXPFJA-HNAYVOBHSA-N
PubChem ID219101
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <16,H;Hydroxylation;R1>
  • <17,H;Hydroxylation;R2>
  • Not Available
  • Not Available
References
  1. Johnson K, Shah A, Jaw-Tsai S, Baxter J, Prakash C: Metabolism, pharmacokinetics, and excretion of a highly selective N-methyl-D-aspartate receptor antagonist, traxoprodil, in human cytochrome P450 2D6 extensive and poor metabolizers. Drug Metab Dispos. 2003 Jan;31(1):76-87. doi: 10.1124/dmd.31.1.76. [PubMed:12485956 ]
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