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Showing CypComp Card for CC02305: Yohimbine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:50 UTC
Last Updated2019-10-01 21:41:50 UTC
CypComp IDCC02305
Compound Information
NameYohimbine
Structure ImageBlgxfzzntvwlay cczxdcjgsa n
InChIKeyBLGXFZZNTVWLAY-CCZXDCJGSA-N
PubChem ID21603871
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <17,H;Hydroxylation;R1>
  • <18,H;Hydroxylation;R2>
  • Not Available
  • <17,H;Hydroxylation;R1>
  • <18,H;Hydroxylation;R2>
References
  1. Le Corre P, Parmer RJ, Kailasam MT, Kennedy BP, Skaar TP, Ho H, Leverge R, Smith DW, Ziegler MG, Insel PA, Schork NJ, Flockhart DA, O'connor DT: Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism. Clin Pharmacol Ther. 2004 Aug;76(2):139-53. doi: 10.1016/j.clpt.2004.04.010. [PubMed:15289791 ]
Download FileCC02305.sdf