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Showing CypComp Card for CC02311: CJ-12 458 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:52 UTC
Last Updated2019-10-01 21:41:51 UTC
CypComp IDCC02311
Compound Information
NameCJ-12 458
Structure ImageCvtmennexozzez iowsjchksa n
InChIKeyCVTMENNEXOZZEZ-IOWSJCHKSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <32,34;EpOxidation;R1>
  • <32,34;Reduction;R2>
  • <34,H;Hydroxylation;R2>
  • Not Available
  • <32,34;EpOxidation;R1>
  • <32,34;Reduction;R2>
  • <34,H;Hydroxylation;R2>
References
  1. Obach RS: Cytochrome P450-catalyzed metabolism of ezlopitant alkene (CJ-12,458), a pharmacologically active metabolite of ezlopitant: enzyme kinetics and mechanism of an alkene hydration reaction. Drug Metab Dispos. 2001 Jul;29(7):1057-67. [PubMed:11408374 ]
Download FileCC02311.sdf