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Showing CypComp Card for CC02313: Desimipramine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:52 UTC
Last Updated2019-10-01 21:41:51 UTC
CypComp IDCC02313
Compound Information
NameDesimipramine
Structure ImageHcyafaltsjyzdh uhfffaoysa n
InChIKeyHCYAFALTSJYZDH-UHFFFAOYSA-N
PubChem ID2995
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <19,H;Hydroxylation;R1>
  • <20,H;Hydroxylation;R2>
  • Not Available
  • Not Available
References
  1. von Moltke LL, Greenblatt DJ, Cotreau-Bibbo MM, Duan SX, Harmatz JS, Shader RI: Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo. J Pharmacol Exp Ther. 1994 Mar;268(3):1278-83. [PubMed:8138941 ]
Download FileCC02313.sdf