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Showing CypComp Card for CC02316: Raloxifene (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:37:53 UTC
Last Updated2019-10-01 21:41:51 UTC
CypComp IDCC02316
Compound Information
NameRaloxifene
Structure ImageGzuitabiakmvpg uhfffaoysa n
InChIKeyGZUITABIAKMVPG-UHFFFAOYSA-N
PubChem ID5035
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <3,H;Hydroxylation;R1>
  • <5,H;Hydroxylation;R2>
  • <30,H;Hydroxylation;R3>
  • <32,H;Hydroxylation;R4>
  • Not Available
  • Not Available
References
  1. Chen Q, Ngui JS, Doss GA, Wang RW, Cai X, DiNinno FP, Blizzard TA, Hammond ML, Stearns RA, Evans DC, Baillie TA, Tang W: Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation. Chem Res Toxicol. 2002 Jul;15(7):907-14. [PubMed:12119000 ]
Download FileCC02316.sdf