You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on CypComp Database.
Record Information
Version1.0
Creation Date2019-07-14 16:37:55 UTC
Last Updated2019-10-01 21:41:52 UTC
CypComp IDCC02323
Compound Information
NameBenzene
Structure ImageUhovqnzjysornb uhfffaoysa n
InChIKeyUHOVQNZJYSORNB-UHFFFAOYSA-N
PubChem ID241
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <1,H;Hydroxylation;R1>
  • <2,H;Hydroxylation;R2>
  • <3,H;Hydroxylation;R3>
  • <4,H;Hydroxylation;R4>
  • <5,H;Hydroxylation;R5>
  • <6,H;Hydroxylation;R6>
  • <1,2;EpOxidation;R7>
  • <2,3;EpOxidation;R8>
  • <3,4;EpOxidation;R9>
  • <4,5;EpOxidation;R10>
  • <5,6;EpOxidation;R11>
  • <6,1;EpOxidation;R12>
  • Not Available
References
  1. Snyder R, Chepiga T, Yang CS, Thomas H, Platt K, Oesch F: Benzene metabolism by reconstituted cytochromes P450 2B1 and 2E1 and its modulation by cytochrome b5, microsomal epoxide hydrolase, and glutathione transferases: evidence for an important role of microsomal epoxide hydrolase in the formation of hydroquinone. Toxicol Appl Pharmacol. 1993 Oct;122(2):172-81. doi: 10.1006/taap.1993.1185. [PubMed:8211999 ]
Download FileCC02323.sdf