Showing CypComp Card for CC02345: Clarithromycin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:38:00 UTC
Last Updated2019-10-01 21:41:55 UTC
CypComp IDCC02345
Compound Information
NameClarithromycin
Structure ImageAgoydepgaoxock wiqgunghsa n
InChIKeyAGOYDEPGAOXOCK-WIQGUNGHSA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <39,32;Cleavage;R1>
  • <39,H;Oxidation;R1>
  • <40,32;Cleavage;R2>
  • <40,H;Oxidation;R2>
  • <47,H;Hydroxylation;R3>
References
  1. Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D: Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily. Drug Metab Dispos. 1997 May;25(5):623-30. [PubMed:9152603 ]
Download FileCC02345.sdf