Showing CypComp Card for CC02354: ABT-378 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:53:25 UTC
Last Updated2019-10-01 21:41:56 UTC
CypComp IDCC02354
Compound Information
NameABT-378
Structure ImageKjhkthwmrkykje uqjygfkosa n
InChIKeyKJHKTHWMRKYKJE-UQJYGFKOSA-N
PubChem ID6850809
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <14,H;Oxidation;R1>
References
  1. Kumar GN, Dykstra J, Roberts EM, Jayanti VK, Hickman D, Uchic J, Yao Y, Surber B, Thomas S, Granneman GR: Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction. Drug Metab Dispos. 1999 Aug;27(8):902-8. [PubMed:10421617 ]
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