Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:53:29 UTC |
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Last Updated | 2019-10-01 21:41:59 UTC |
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CypComp ID | CC02370 |
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Compound Information |
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Name | Colchicine |
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Structure Image | |
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InChIKey | IAKHMKGGTNLKSZ-MRXNPFEDSA-N |
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PubChem ID | 53278 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | - <8,7;Cleavage;R1>
- <8,H;Oxidation;R1>
- <10,9;Cleavage;R2>
- <10,H;Oxidation;R2>
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References | - Tateishi T, Soucek P, Caraco Y, Guengerich FP, Wood AJ: Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation. Biochem Pharmacol. 1997 Jan 10;53(1):111-6. doi: 10.1016/s0006-2952(96)00693-4. [PubMed:8960070 ]
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Download File | CC02370.sdf |
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