Showing CypComp Card for CC02375: Cyclosporine A (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:53:30 UTC
Last Updated2019-10-01 21:42:00 UTC
CypComp IDCC02375
Compound Information
NameCyclosporine A
Structure ImagePmatztznyrchor uittwsbisa n
InChIKeyPMATZTZNYRCHOR-UITTWSBISA-N
PubChem IDNot Available
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <71,H;Hydroxylation;R1>
  • <60,15;Cleavage;R2>
  • <60,H;Oxidation;R2>
  • <67,H;Hydroxylation;R3>
References
  1. Dai Y, Iwanaga K, Lin YS, Hebert MF, Davis CL, Huang W, Kharasch ED, Thummel KE: In vitro metabolism of cyclosporine A by human kidney CYP3A5. Biochem Pharmacol. 2004 Nov 1;68(9):1889-902. doi: 10.1016/j.bcp.2004.07.012. [PubMed:15450954 ]
Download FileCC02375.sdf